Chronic Obstructive Pulmonary Disease (COPD)
Conditions
Interventions
Adaptive Statistical Iterative Reconstruction-V at 50% strength (ASiR-V50%) group:None
Deep Learning Image Reconstruction at Medium Level (DLIR-M) group:None
Filtered back projection (FBP) group:None
Deep Learning Image Reconstruction at Low Level (DLIR-L) group:None
Sponsors
The First Affiliated Hospital of Henan University of Science and Technology
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Adults aged >=18 years with a diagnosis of COPD, confirmed according to the 2025 GOLD guidelines. 2. Completion of both pulmonary function tests (PFT) and biphasic (inspiratory/expiratory) non-contrast chest CT scans on a GE Healthcare 256-slice CT scanner during the same clinical visit. 3. Availability of complete imaging and clinical data suitable for paired analysis.
Exclusion criteria
Exclusion criteria: 1. Patients with images exhibiting significant motion artifacts, severe metal artifacts, or other artifacts that compromise the quality of quantitative analysis and diagnostic interpretation. 2. Patients unable to cooperate with breathing instructions during the CT scan. 3. Patients with concurrent severe pulmonary diseases, such as pulmonary fibrosis or active tuberculosis.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pulmonary function parameters;CT quantitative parameters; | — |
Secondary
| Measure | Time frame |
|---|---|
| CT quantitative parameters; | — |
Countries
China
Contacts
Public ContactQiang Jun
The First Affiliated Hospital of Henan University of Science and Technology
Outcome results
None listed