postpartum depression
Conditions
Interventions
Group C:Group C received 15 ml of 1% ropivacaine diluted to 150 ml with saline. The analgesic device is set as follows: Pulse infusion of 10 ml, with each pulse interval set at 1 hour. Patient-control
Group E:Group E received 15 ml of 1% ropivacaine plus 0.2 mg·kg?1 esketamine diluted to 150 ml with saline. The analgesic device is set as follows: Pulse infusion of 10 ml, with each pulse interval se
Group D:Group D received 15 ml of 1% ropivacaine plus 0.5 µg·kg?1 dexmedetomidine diluted to 150 ml with saline. The analgesic device is set as follows: Pulse infusion of 10 ml, with each pulse interv
Group ED:The ED group received the following treatment: 15 ml of 1% ropivacaine plus 0.1 mg·kg-1 esketamine and 0.25 µg·kg-1 dexmedetomidine diluted to 150 ml. The analgesic device is set as follows:
Sponsors
First People’s Hospital of Yinchuan
Eligibility
Sex/Gender
Female
Age
20 Years to 40 Years
Inclusion criteria
Inclusion criteria: 1. Aged 20–40 years; 2. Healthy primiparous women with singleton, full-term pregnancies (>=37 weeks); 3. Voluntarily undergoing epidural analgesia for labour; 4. ASA physical status classification of grade II; 5. Possessing a secondary education or higher, capable of completing questionnaire assessments, and able to sign an informed consent form.
Exclusion criteria
Exclusion criteria: 1. Individuals with cardiac, hepatic, or renal insufficiency; 2. Individuals with coagulation disorders; 3. Pregnant women with complications such as hypertension or diabetes; 4. Individuals with a history of mental illness or mental illness during pregnancy; 5. Individuals with a history of depression or depression during pregnancy; 6. Individuals with allergies to anaesthetic drugs; 7. Individuals who did not deliver vaginally after receiving epidural analgesia for labour; 8. Individuals requesting withdrawal from the study; 9. Individuals with incomplete clinical data collection.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Edinburgh Postnatal Depression Scale Assessment; | — |
Secondary
| Measure | Time frame |
|---|---|
| number rating score at rest;Analgesic pump medication usage;number of patient-controlled epidural analgesia (PCEA) bolus requests;Dosage of each medication;Duration of labour;Apgar score at 1 minute after delivery;Total blood loss within 2 hours postpartum;epinephrine;norepinephrine;Cortisol;brain-derived neurotrophic factor; | — |
Countries
China
Contacts
Public ContactMa Jie
First People’s Hospital of Yinchuan, The Second Clinical Medical College of Ningxia Medical University
Outcome results
None listed