Prolonged DoC
Conditions
Interventions
Experimental group:tDCS plus MNS stimulation (5 days per week with 2 days of rest for 2 weeks)
Control group:tDCS stimulation
Sponsors
The Affiliated Rehabilitation Hospital of Zhejiang Chinese Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1.Those aged 18-80 years old; 2.Those diagnosed with UWS and MCS based on the CRS-R scale; 3. 28 days < course of illness < 2 years; 4.Causes include ischemic-hypoxic encephalopathy, traumatic brain injury, stroke, etc.; 5.Right-handers.
Exclusion criteria
Exclusion criteria: 1. Deafness; 2. Psychiatric or neurological disorders; 3.Infectious or metabolic brain injury; 4. Locked-in syndrome; 5. Those who take stimulant drugs that affect the cortex; 6.There are intracranial artery clips, pacemakers, nerve stimulators, etc. 7. Hearing and eye movement disorders. 8. Individuals with uncontrollable epilepsy or involuntary movements.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Near-infrared brain function(fNIRS) indicators;EEG indicators;Recovery from coma; | — |
Countries
China
Contacts
Public ContactZhang Shuijing
The Affiliated Rehabilitation Hospital of Zhejiang Chinese Medical University/ Zhejiang Rehabilitation Medical Center
Outcome results
None listed