None listed
Conditions
Interventions
Test group:Subjects will receive the investigational product for 28 days.
Sponsors
Central Hospital of Fengxian District, Shanghai
Eligibility
Sex/Gender
All
Age
25 Years to 45 Years
Inclusion criteria
Inclusion criteria: (1) Healthy women aged between 25 and 45; (2) Visual assessment of periorbital wrinkles in volunteers conducted by trained personnel who have passed wrinkle grading evaluation, with wrinkle severity meeting the criteria of the "Evaluation Standard for Human Skin Aging" at grade >= 2; (3) Facial skin laxity and loss of elasticity; (4) Individual typology angle (ITA° value) = 3 according to the facial skin yellowness reference scale; (6) Able to read Chinese, accurately understand the trial procedures, voluntarily participate in the trial, and sign the informed consent form; willing and able to comply with follow-up visits, promptly report any changes in their health status or regarding the test product, adverse reactions, and adhere to all study requirements and scheduled timelines.
Exclusion criteria
Exclusion criteria: (1) Individuals who are currently pregnant or lactating, or planning to become pregnant during the test period; (2) Individuals who may be allergic to the test sample or its ingredients; (3) Patients with severe diseases of the heart, liver, kidneys, hematopoietic system, or other major organs; (4) Individuals with mental disorders, serious endocrine diseases, or those taking oral contraceptives; (5) Individuals with facial skin conditions that may affect evaluation of the test results; (6) Individuals who have taken or used products related to the tested function within the past month (e.g., dietary supplements such as vitamin C, berries, flavonoids; antioxidant medications such as vitamin E, vitamin C, etc.), which may influence result assessment; (7) Individuals who have participated in other clinical trials within the past month; (8) Individuals who do not meet inclusion criteria, did not consume the test sample as instructed, or whose efficacy or safety cannot be evaluated due to incomplete data; (9) Individuals deemed unsuitable for participation by clinical evaluation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Facial image capture and analysis;Skin elasticity R2;Skin luster;Skin brightness L* value;Skin stratum corneum water content value;TEWL (Trans Epidermal Water Loss);ITA° value of skin color;Skin melanin content;Dermal density;Skin yellowness b* value;AGEs levels; | — |
Secondary
| Measure | Time frame |
|---|---|
| Vital signs; | — |
Countries
China
Contacts
Public ContactZhu Haiying
Central Hospital of Fengxian District, Shanghai
Outcome results
None listed