diabetes
Conditions
Interventions
The group receiving only insulin:Only using insulin-based medications (such as rapid-acting, premixed, long-acting insulins, etc.) for blood sugar control, without combining other types of hypoglycemi
The group treated with metformin and insulin:The combination of metformin and insulin-based drugs is used for hypoglycemic treatment, without additional use of other types of hypoglycemic drugs (such
The group treated with empagliflozin10mg + Insulin:The treatment for lowering blood sugar was carried out using 10mg of empagliflozin in combination with insulin drugs, without additional use of other
Sponsors
Tianjin Medical University Chu Hsien-I Memorial Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. At least 18 years old; 2. Meets the diagnostic criteria for type 2 diabetes as stipulated in the 2020 CDS guidelines, with the diagnosis made within less than 3 months; 3. Initiates insulin treatment for the first time; 4. At the time of diagnosis, fasting blood glucose is greater than 10 mmol/L, and HbA1c is greater than 9.0% 5. Voluntarily participates in and cooperates with the study and signs the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Combined with severe acute complications such as ketoacidosis; 2. Incompatible conditions for the use of SGLT inhibitors and metformin; 3.Patients with severe liver and kidney damage; 4. Pregnant or expecting pregnant patients; 5. Patients who are unwilling to participate in this trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| HbA1c; | — |
Secondary
| Measure | Time frame |
|---|---|
| Self-Monitoring of Blood Glucose, SMBG;Insulin Dose;Grade 2 and Grade 3 Hypoglycemia Incidence and Rate;Grade 2 and Grade 3 Nocturnal Hypoglycemia Incidence and Rate; Body Weight;Lipid Profile;Uric Acid;Urine Albumin-to-Creatinine Ratio;Renal Oxygenation Level;Number of Patients with Diabetes Reversal; | — |
Countries
China
Contacts
Public ContactLi Jing
Tianjin Medical University Chu Hsien-I Memorial Hospital
Outcome results
None listed