Non-suicidal self-injury refers to the deliberate act of harming one's own body, such as cutting or burning oneself. Generally speaking, this type of self-harm does not mean that someone is attempting suicide, but rather a harmful way to cope with emotional pain, sadness, anger, and stress.
Conditions
Interventions
TI intervention group:Two pairs of high-frequency currents are applied to produce interference, with carrier frequencies (carrier frequencies) set at f1 = 2000 Hz and f2 = 2040 Hz, respectively. This
Healthy control group:None
SHAM intervention group:Participants in the sham stimulation group will undergo exactly the same external procedures as those in the real stimulation group, including target localization, electrode pl
however, during the entire 20-minute main intervention period, no effective envelope waveform is generated, meaning there is no sustained neuromodulation of deep target regions. The stimulation freque
Sponsors
Affiliated Kangning Hospital of Ningbo University
Eligibility
Sex/Gender
All
Age
16 Years to 55 Years
Inclusion criteria
Inclusion criteria: 1. Aged 16–55 years, gender unlimited; 2. Meeting any mental illness diagnosis in DSM-5 and accompanied by NSSI behaviors; 3. Having at least 3 episodes of NSSI behaviors within the past 6 months; 4. Right-handed; 5. Able to understand and voluntarily sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. There is a serious risk of suicide; 2. A history of neurological disorders (such as epilepsy, brain injury, stroke, etc.); 3. Presence of metallic implants (such as pacemakers, metal dental prosthetics, aneurysm clips, etc.) or other MRI contraindications; 4. A history of alcohol or substance abuse/dependence (except nicotine); 5. Undergoing other physical treatments (such as ECT, rTMS); 6. Pregnant or lactating women; 7. Or any other conditions that the researcher deems unsuitable for participation in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Deliberate Self-Harm Scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| Snaith-Hamilton Pleasure Scale;MADRS;Difficulties in Emotion Regulation Scale;Beck Depression and Anxiety Inventory;Simple Gambling Task;Resting-state fMRI (rs-fMRI);Diffusion Tensor Imaging;Amplitude of Low-Frequency Fluctuations / Regional Homogeneity;Brain Network Graph Theory Metrics; | — |
Countries
China
Contacts
Public ContactChen Haocheng
Affiliated Kangning Hospital of Ningbo University
Outcome results
None listed