Weichteilschmerzen
Conditions
Interventions
Compound Betamethasone Injection Group:Compound Betamethasone Injection
Dexamethasone Palmitate Injection Group:Dexamethasone Palmitate Injection
Sponsors
Zhejiang Provincial Hospital of TCM
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1.Age range: 18-80 years old, gender is not limited; 2.It meets the relevant diagnostic criteria for acute and chronic soft tissue pain diseases or neuropathic pain. Soft tissue pain diseases with a history of less than 4 weeks are defined as acute, and those with a history of 4 weeks or more are defined as chronic. Neuropathic pain with a history of >=3 months is defined as chronic; 3.The average NRS score for pain intensity in the target area is >=4 points; 4.Poor response, intolerance, or contraindications to conventional conservative treatments (such as medication, physical therapy, etc.); 5.Voluntarily participate in this study, understand the research process, and sign a written informed consent form;
Exclusion criteria
Exclusion criteria: 1.Absolute contraindications: Active infection, ulceration, or tumor at the puncture site; 2.Drug allergy: Known hypersensitivity to the investigational drugs (dexamethasone palmitate, compound betamethasone, or any excipient components) or to the local anesthetics used; 3.Severe systemic diseases: Presence of uncontrolled severe systemic conditions (e.g., heart failure, severe hepatic or renal insufficiency, uncontrolled hypertension/diabetes mellitus); 4.Coagulopathy: Significant coagulation abnormalities (INR >1.5, APTT >1.5 times the upper limit of normal, platelet count <50×10?/L), coagulopathies such as hemophilia, or current use of anticoagulant/antiplatelet medications that cannot be safely withheld for the required duration prior to the procedure. 5.Special populations: Pregnant or lactating women; 6.Cognitive and functional impairment: Severe cognitive or psychiatric disorders that preclude cooperation with evaluation and follow-up procedures; 7.Previous treatment: Having received corticosteroid injection therapy in the target area within the preceding 3 months;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| numerical rating scale (NRS);Zeitraum zwischen der ersten Behandlung und dem Wiederauftreten der Schmerzen (NRS >= 4 Punkte und mindestens 24 Stunden andauernd) oder der Notwendigkeit weiterer medizinischer Ma?nahmen (wie Medikamente, Physiotherapie oder erneute Injektion); | — |
Countries
China
Contacts
Public ContactZhang juan
Zhejiang Provincial Hospital of TCM
Outcome results
None listed