Atopic dermatitis
Conditions
Interventions
Moderate-to-Severe AD (Biologics or JAK Inhibitor Treatment Group):None
AD (Non-biologics or JAK Inhibitor Treatment Group):None
Sponsors
Huashan Hospital, Fudan University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1.Meeting the Chinese diagnostic criteria for atopic dermatitis (Electronic Medical Record Registration Study and Prospective Cohort Study on Moderate to Severe AD); 2.No age or gender restrictions (Electronic Medical Record Registration Study); 3.Voluntarily sign the informed consent form (Electronic Medical Record Registration Study and Prospective Cohort Study on Moderate to Severe AD); 4.Age >= 12 years (Prospective Cohort Study on Moderate to Severe AD); 5.Candidates for treatment with biologic agents or JAK inhibitors (Prospective Cohort Study on Moderate to Severe AD); 6.At the baseline visit, IGA >= 3 (on the 0-4 IGA scale, where 3 is moderate and 4 is severe) or EASI >= 7 (Prospective Cohort Study on Moderate to Severe AD);
Exclusion criteria
Exclusion criteria: 1.Unwillingness to sign the informed consent form;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The proportion of subjects who achieved EASI-75 at Week 48;The proportion of subjects who achieved EASI-75 at Week 12; | — |
Secondary
| Measure | Time frame |
|---|---|
| Proportion of subjects with IgA score of 0 or 1 and a decrease of >= 2 points from baseline;Proportion of subjects whose IgA score decreased by >= 2 points from baseline;Proportion of subjects reaching easi-90 and easi-50;Proportion of subjects whose pp-nrs decreased by >= 4 points from baseline;Easi change from baseline and percentage change;ADCT change from baseline and percentage change; | — |
Countries
China
Contacts
Public ContactGu Chaoying
Huashan Hospital, Fudan University
Outcome results
None listed