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Development of a Predictive Model and Its Underlying Mechanisms for Intrapartum Fever in Parturients Receiving Epidural Analgesia Based on Clinical Features

Development of a Predictive Model and Its Underlying Mechanisms for Intrapartum Fever in Parturients Receiving Epidural Analgesia Based on Clinical Features

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600116162
Enrollment
Unknown
Registered
2026-01-06
Start date
2026-01-09
Completion date
Unknown
Last updated
2026-01-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

epidural-related maternal fever

Interventions

Sponsors

Shenzhen Longgang District Maternal and Child Healthcare Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: 1. Retrospective Study All parturients who received epidural labor analgesia from January 1, 2021, to December 31, 2024. 2. Prospective Study (1) ASA II–III; (2) Full-term pregnancy; (3) Parturients scheduled for vaginal delivery under epidural anesthesia.

Exclusion criteria

Exclusion criteria: 1. Patients with contraindications to painless delivery; 2. Patients who had a fever before delivery; 3. Patients with immunodeficiency diseases or autoimmune diseases; 4. Patients with any possible sterile or infectious inflammation; 5. Those who have taken antibiotics or hormone medications in the past month; 6. Other pregnant women deemed unsuitable for inclusion in the study by the researchers.

Design outcomes

Primary

MeasureTime frame
CCL3/MiP-1 alpha;CCL4/MiP-1 beta;CD25/lL-2R alpha;GM-CSF;lFN-gamma;lL-1 beta;IL-2;IL-4;IL-5;IL-6;1L-8/CXCL8;IL-10;IL-12/IL-23 p40;IL-17/IL-17A;TNF-alpha;mRNA;

Countries

China

Contacts

Public ContactZhao Yang

Shenzhen Longgang District Maternal and Child Healthcare Hospital

lgfymz@163.com+86 186 0300 7033

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026