Obesity and Metabolic Diseases
Conditions
Interventions
Control group:Simple sleeve gastrectomy
Experimental group:Sleeve gastrectomy combined with His angle reconstruction
Sponsors
Chengdu Third People's Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Age >18 years and = 32.5 kg/m^2; (2) BMI >= 27.5 kg/m^2 but =90 cm, female waist circumference >= 85 cm, with imaging indicating central obesity; after MDT assessment and ethical approval, the surgical recommendation level can be adjusted accordingly; (4) Patients with 25 kg/m^2 <=BMI < 27.5 kg/m^2 and T2DM who have difficulty controlling blood glucose through lifestyle changes and medication and have obesity-related comorbidities; their insulin secretory function should be evaluated, and surgery can be performed after MDT assessment and ethical approval. 3. No major organ dysfunction, no neuropsychiatric disorders, and no other harmful habits. 4. Informed consent obtained with good compliance, and able to cooperate and complete the study.
Exclusion criteria
Exclusion criteria: 1. Preoperative diagnosis of gastroesophageal reflux disease (GERD); 2. Use of anti-reflux medications (e.g., proton pump inhibitors [PPIs], H2-receptor antagonists) within 1 month prior to surgery; 3. History of anti-reflux surgery or upper abdominal surgery; 4. Pregnancy or lactation; 5. Intraoperative findings of hiatal hernia or other pathologies requiring intervention; 6. Severe cardiocerebrovascular diseases or major organ dysfunction contraindicating surgery or general anesthesia.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Gastroesophageal Reflux Scale Score; | — |
Countries
China
Contacts
Public ContactLiu Yanjun
Chengdu Third People's Hospital
Outcome results
None listed