postoperative cognitive dysfunction
Conditions
Interventions
Experimental group:Implementing refined anesthesia management,Application of esketamine
Control group:Sufentanil
Sponsors
Jiangsu NanTong,Rugao People’s Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: (1) Elderly patients undergoing surgical treatment; (2) Able to complete the Fried Frailty Assessment Tool; (3) Be capable of completing the CAM cognitive function assessment tool; (4) Family members and patients consent to participate in this study.
Exclusion criteria
Exclusion criteria: (1) The patient or the patient's family refused to participate in this study; (2) Complicated with organic brain diseases, such as brain trauma, intracranial hematoma, or congenital brain developmental abnormalities; (3) Those with preoperative delirium or cognitive dysfunction; (4) Patients with dementia or known mental disorders; (5) Patients with aphasia or hearing impairment; (6) Patients who did not sign the informed consent form or were lost to follow-up.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Confusion Assessment Method(CAM);Hamilton Depression Scale(HAMD);Interleukin-6; | — |
Secondary
| Measure | Time frame |
|---|---|
| Tumor Necrosis Factor-a;Visual Analog Scale; | — |
Countries
China
Contacts
Public ContactYingmei Ren
Rugao People’s Hospital, Rugao 226500, China
Outcome results
None listed