lung surgery
Conditions
Interventions
Group F:Fixed Low Tidal Volume
Group I:Individualized Tidal Volume
Sponsors
The First Affiliated Hospital of Anhui Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Patients scheduled for elective video-assisted thoracoscopic partial pulmonary resection under general anesthesia, with a body mass index (BMI) between 24 and 35 kg/m². 2. Age 18 to 75 years, irrespective of gender. 3. American Society of Anesthesiologists (ASA) physical status classification I-III. 4. Informed of and willing to participate in the trial, having provided written informed consent.
Exclusion criteria
Exclusion criteria: 1. Severe pulmonary diseases, such as chronic obstructive pulmonary disease (COPD) with a GOLD classification >2, severe asthma, or a history of pneumothorax, which may affect pulmonary compliance. 2. Severe cardiac (New York Heart Association [NYHA] class III or IV), hepatic (Child-Pugh score 10-15), renal (requiring renal replacement therapy), or hematopoietic system diseases (e.g., leukemia). 3. Conditions that make lung ultrasound difficult to perform (e.g., chest wall fracture, thoracic deformity). 4. History of previous pulmonary surgery. 5. History of upper respiratory tract infection within two weeks prior to surgery. 6. Participation in other clinical trials within the past three months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence of atelectasis 30 minutes after extubation; | — |
Secondary
| Measure | Time frame |
|---|---|
| LUS scores at 30 minutes post-extubation and 24 hours postoperatively ;Hemodynamic parameters ;Incidence of hypoxemia ;Postoperative pulmonary complications;Oxygenation index; | — |
Countries
China
Contacts
Public ContactLijian Chen
The First Affiliated Hospital of Anhui Medical University
Outcome results
None listed