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Different doses of Afentanil combined EP mixture for painless gastrointestinal endoscopy application.

Different doses of Afentanil combined EP mixture for painless gastrointestinal endoscopy application.

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600116104
Enrollment
Unknown
Registered
2026-01-05
Start date
2025-04-17
Completion date
Unknown
Last updated
2026-01-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None

Interventions

A:During anesthesia induction, group A was given 3 µg/kg of alfentanil
B:During anesthesia induction, group B was given 5 µg/kg of alfentanil
C:During anesthesia induction, group C was given 7 µg/kg of alfentanil

Sponsors

Yanan University Affiliated Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 64 Years

Inclusion criteria

Inclusion criteria: 1. Age: 18-64 years, 2. BMI: 18-25 kg/m^2, 3. ASA classification ? or ? by the American Society of Anesthesiologists, 4.Patients scheduled for painless gastrointestinal endoscopy.

Exclusion criteria

Exclusion criteria: 1. Dysfunction of important organs such as the liver, kidneys, heart, lungs, and brain, 2. Recent use of sedative and analgesic medications, 3. Allergic constitution or known allergy to the experimental drug.

Design outcomes

Primary

MeasureTime frame
The incidence of subclinical hypoxemia (90% = SpO2 < 95%);Mean arterial pressure;

Secondary

MeasureTime frame
Related times for gastrointestinal endoscopy (time of entry, interval time for first additional fentanyl, total time of gastrointestinal endoscopy, awakening time, time to leave the room);Occurrence of adverse reactions during anesthesia (coughing, hiccups, hypotension, movement responses, hypoxemia, bradycardia);Occurrence of adverse reactions (headache, nausea, vomiting, drowsiness) 24h, 48h, and 72h after surgery.;Blood pressure;Heart rate;Oxyhemoglobin saturation;

Countries

China

Contacts

Public ContactZhikai Luo

Yanan University Affiliated Hospital

lzk1821@126.com+86 138 9117 1821

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026