Sepsis in children
Conditions
Interventions
Trial group:None
Sponsors
Shengjing Hospital Affiliated to China Medical University
Eligibility
Sex/Gender
All
Age
No minimum to 14 Years
Inclusion criteria
Inclusion criteria: (1) Between 29 days and 14 years old; (2) Meet the 2020 version of the international SAOD diagnostic criteria for children: severe infection leading to cardiovascular and/or non-cardiovascular organ dysfunction; (3) Confirmed SAOD within 24 hours.
Exclusion criteria
Exclusion criteria: (1) The child dies or is discharged within 2 hours after admission; (2) Children with shock caused by other reasons; (3) The child is in the active stage of immune disease, has bone marrow suppression or is using chemotherapy drugs; (4) Children with liver, kidney and other organ failure before infection.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Glasgow Coma Scale;Pediatric Risk of Mortality III;Pediatric Logistic Organ Dysfunction-2;Method of Pediatric Critical Illness Score;Potential of Hydrogen;Partial Pressure of Carbon Dioxide;Partial Pressure of Oxygen;Potassium ion;Sodium ion;Base Excess;Prothrombin Time;Activated Partial Thromboplastin Time;International Normalized Ratio;Fibrinogen;Interleukin-6;D-dimer;C-reactionprotein;Cardiac Troponin I;procalcitonin;White Blood Cell Count;Systolic Blood Pressure;mean blood pressure;Heart Rate;Lactic Acid;Total Bilirubin;Albumin;Alanine Aminotransferase;Aspartate Aminotransferase;Creatinine;Blood Urea Nitrogen;Creatine Kinase;N-terminal pro B-type natriuretic peptide;Respiratory Rate;Platelet;NeutroPhil Percentage;Hemoglobin;Glucose;Temperature; | — |
Countries
China
Contacts
Public ContactYang Ni
Shengjing Hospital Affiliated to China Medical University
Outcome results
None listed