Colorectal cancer (CRC)
Conditions
Interventions
Early to mid-stage (0, I, II):N/A
Late stage (III, IV):N/A
Sponsors
The Second Affiliated Hospital of Dalian Medical University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.Age >18 years; 2.Diagnosis of primary colorectal cancer consistent with the Chinese Society of Clinical Oncology (CSCO) Clinical Guidelines for Colorectal Cancer (2025); 3.Newly diagnosed with primary colorectal cancer, or with a previous diagnosis but having received no prior anti-tumor therapy; 4.Provision of written informed consent; 5.Availability of complete medical records and demonstrated compliance throughout the study period.
Exclusion criteria
Exclusion criteria: 1.Age < 18 years; 2.Patients with a prior diagnosis of primary colorectal cancer who had received any related treatment; 3.Patients with secondary (metastatic) colorectal cancer; 4.Patients with a history of other malignancies who had received any prior anti-tumor therapy; 5.Patients who had undergone neoadjuvant therapy (e.g., chemotherapy, radiotherapy, targeted therapy) prior to surgery; 6.Patients with other severe comorbidities that contraindicated surgery or the required procedures.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Comparative Analysis of the Key Bacterium's Relative Abundance in Normal, Adjacent, and Tumor Tissues;Whether there was a significant difference in the relative abundance of the key bacterium between patients with early-stage (0, I, II) and late-stage (III, IV) colorectal cancer.;The relative abundance of the key bacterium was linearly associated with a poor prognosis in colorectal cancer; | — |
Countries
China
Contacts
Public ContactLiming Wang
The Second Affiliated Hospital of Dalian Medical University
Outcome results
None listed