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Application of Optical Coherence Elastography/Tomography in Iris Feature Analysis and Early Diagnosis of Glaucoma

Application of Optical Coherence Elastography/Tomography in Iris Feature Analysis and Early Diagnosis of Glaucoma

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600116057
Enrollment
Unknown
Registered
2026-01-05
Start date
2026-01-06
Completion date
Unknown
Last updated
2026-01-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Glaucoma

Interventions

Healthy control group:None

Sponsors

The First Hospital of Nanchang
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Subjects aged 6 years or older; 2. Diagnosed with glaucoma by an experienced glaucoma specialist, including primary open-angle glaucoma, secondary glaucoma, primary angle-closure glaucoma, developmental glaucoma, and mixed glaucoma; 3. With or without glaucomatous optic nerve structural or visual field changes; 4. Able to cooperate with examinations and fixate on the point light source in instruments such as OCE/OCT; 5. May have cataracts that do not affect the quality of fundus OCT and OCTE examinations; 6. May have corneal opacity or scarring that does not affect the quality of OCE/OCT examinations; 7. May or may not have systemic diseases. Inclusion criteria for the control group: (1) No optic nerve structural changes or visual field defects; (2) IOP < 21 mmHg; (3) Cup-to-disc ratio < 0.6 and inter-eye cup-to-disc ratio difference < 0.2; (4) Normal anterior and posterior segment eye examinations; (5) No family history of glaucoma.

Exclusion criteria

Exclusion criteria: 1. Structural or visual field changes in the optic nerve not caused by glaucoma; 2. Anterior segment OCT and OCTA examinations affected by corneal leukoma; 3. Poor image quality due to poor patient cooperation.

Design outcomes

Primary

MeasureTime frame
Differences in iris biological indicators between the exposed group and the experimental group;

Countries

China

Contacts

Public ContactYingjie Li

The First Hospital of Nanchang

xljlyj@163.com+86 791 8886 2468

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026