Stroke
Conditions
Interventions
Control Group:Routine cognitive training consists of paper-and-pencil or computer-based tasks, covering various training methods targeting memory, computational ability, attention, apraxia, and other
Experimental Group:On the basis of conventional intervention, additional immersive virtual reality (VR) training is provided, including immersive scenario training, motor perception training, memory s
Sponsors
Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1.First episode of unilateral ischemic or hemorrhagic stroke confirmed by MRI or CT, in accordance with the definition of the World Health Organization (WHO). 2.Aged 18 to 70 years, with no gender restriction. 3.The time of first onset ranges from March to June. 4.Score on the Montreal Cognitive Assessment (MoCA) ranging from 18 to 25 points, indicating mild cognitive impairment. 5.No severe visual or auditory impairment, or with mild visual/auditory impairment that does not affect cooperation in completing VR training. 6.Voluntary participation in the study and provision of written informed consent.
Exclusion criteria
Exclusion criteria: 1 .Exclude patients with sensory or motor dysfunction that may interfere with VR intervention. 2. Intolerance to virtual reality equipment (e.g., motion sickness, history of epilepsy). 3 .Presence of contraindications to fMRI or EEG examinations (e.g., cardiac pacemaker, intracranial metallic foreign bodies, skin infection, etc.). 4. A history of cognitive impairment caused by mental illness, neurological diseases, internal medical conditions, or substance abuse. 5 .Special physiological status: pregnant or lactating women.4.6 Concurrent participation in other clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Montreal Cognitive Assessment; | — |
Secondary
| Measure | Time frame |
|---|---|
| Mini-Mental State Examination, MMSE;Stroop Color and Word Test, SCWT;Logical Memory Test, LMT;Symbol Digit Modalities Test, SDMT;Trail Making Test, TMT ;Hamilton Anxiety Scale, HAMA;Hamilton Depression Scale, HAMD;Functional Magnetic Resonance Imaging, fMRI;Electroencephalogram, EEG; | — |
Countries
China
Contacts
Public ContactHua Xuyun
Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine
Outcome results
None listed