Thoracic Subacute Herpetic Neuralgia
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Age: 18 to 80 years old; 2. body mass index (BMI) : 18.5-30 kg/m ²; 3. American Society of Anesthesiologists (ASA) grade I to III; 4. It conforms to the definition of SHN in the "Expert Consensus on Diagnosis and Treatment of Herpes Zoster in China (2022 Edition)", with a disease course of 1 to 3 months; 5. The herpes zoster nerves distributed along the T1 to T12 segments are involved; 6. After regular oral administration of standard therapeutic drugs, the VAS score remains at or above 4 points, or adverse reactions of intolerance to the drugs occur; 7. No invasive interventional treatment was performed for SHN before the operation. 8. After admission, short-term Burst spinal cord electrical stimulation (burst-scs) was used for more than 7 days or ultrasound-guided thoracic paravertebral block (TPVB) was performed continuously for more than 7 times.
Exclusion criteria
Exclusion criteria: 1. Severe liver, kidney and heart dysfunction; 2. Patients with chronic pain; 3. Long-term oral analgesics; 4. Combined with lesions of the central nervous system or peripheral nervous system; 5. Those with severe scoliosis, spinal trauma, or surgeries on the cervical, thoracic or lumbar vertebrae; 6. Patients with mental disorders or severe psychological disorders; 7. Patients with chronic insomnia; 8. Pregnant or lactating women; 9. Those who already have electronic implants such as pacemakers in their bodies; 10. Incomplete data and information; 11. Those who combine multiple interventional treatment methods.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Visual Analog Scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| Efficacy assessment;Incidence of PHN;Incidence of breakthrough pain;Mean number of breakthrough pain episodes per day;Incidence of touch-evoked pain;Severity of touch-evoked pain;Pittsburgh sleep quality index;Dosage of pregabalin;Oral morphine equivalent; | — |
Countries
China
Contacts
The First Affiliated Hospital of Nanjing Medical University