Dry eye
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Dry eye patient group Inclusion criteria: 1. Meet the diagnostic criteria of dry eye in "Chinese Expert Consensus on dry eye: Examination and Diagnosis (2020)" (see Appendix 1). 2. Tears are present and can be removed 3. Voluntarily participated in this study and signed written informed consent. Non-dry eye group Inclusion criteria: 1. Does not meet the diagnostic criteria of dry eye in "Chinese Expert Consensus on dry eye: Examination and diagnosis (2020)" (see Appendix 1). 2. Tears are present and can be removed 3. Voluntarily participated in this study and signed written informed consent.
Exclusion criteria
Exclusion criteria: Dry eye patient group Exclusion criteria: 1. Does not meet the diagnostic criteria of dry eye in "Chinese Expert Consensus on dry eye: Examination and Diagnosis (2020)" (see Appendix 1); 2. Patients with ocular inflammation; 3. History of ocular trauma or surgery in the past three months; 4. Patients who were deemed by the investigator to be ineligible for the study. Non-dry eye group Exclusion criteria: 1. Meet the diagnostic criteria of dry eye in "Chinese Expert Consensus on dry eye: Examination and Diagnosis (2020)" (see Appendix 1); 2. Patients with ocular inflammation; 3. History of ocular trauma or surgery in the past three months; 4. Patients who were deemed by the investigator to be ineligible for the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Tear film break-up time;Chinese dry eye questionnaire score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Thickness of tear film lipid layer;Palpebral margin abnormal score;Meibomian gland related examination results;Missing area of meibomian gland;Intraocular pressure;Sight;Tear meniscus height;DEQS questionnaire score;Subjective and objective scores of tear fern experimental images;Positive rate of tear factors(LTaMMP9);SIT,Schirmer I tset;Corneal fluorescein staining; | — |
Countries
China
Contacts
Zhujiang Hospital of Southern Medical University