Changes in Retinal Microcirculation Following Liver Transplantation
Conditions
Interventions
Observation group of fundus blood flow indicators and liver function after liver transplantation:None
Sponsors
The Third Xiangya Hospital of Central South University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Age between 18 and 70 years old; 2. More than 6 months post-liver transplantation; 3. Sign an informed consent form, voluntarily agree to undergo and cooperate with the examination.
Exclusion criteria
Exclusion criteria: 1. History of ocular diseases: history of ocular trauma, glaucoma, optic atrophy, high myopia or hyperopia, retinal pathology; 2. History of ocular surgery: Vitrectomy, retinal laser photocoagulation, or anti-VEGF therapy 3. Poor macular OCTA imaging quality due to refractive medium opacity caused by corneal haze, advanced cataracts, or vitreous hemorrhage 4. History of cerebrovascular or neurodegenerative diseases (e.g., cerebral infarction, cerebral infarction, Alzheimer's disease) 5. Significant artifacts in manually interpreted raw images 6. Poor patient cooperation during examination 7. Patients with liver transplant failure 8. Patients with hepatocellular carcinoma 9. Patients who have undergone multiple liver transplants or multi-organ transplants
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| Retinal Fractal Dimension;Retinal Vessel Tortuosity;Retinal Capillary Non-Perfusion; | — |
Primary
| Measure | Time frame |
|---|---|
| Retinal vascular density;Foveal Avascular Zone;Retinal flow Index; | — |
Countries
China
Contacts
Public ContactZhihong Deng
The Third Xiangya Hospital of Central South University
Outcome results
None listed