None
Conditions
Interventions
Low-opioid group (experimental group):Preoperative medication: 2-3 hours preoperatively, administer acetaminophen oral solution (10 mg/kg).
Induction phase: Esketon 0.2 mg/kg + dexmedetomidine 0.5-1.0
Traditional group (control group):Preoperative medication: No routine analgesics.
Induction phase: Propofol 2-3 mg/kg + Fentanyl 3 µg/kg + Rocuronium 0.6 mg/kg
Intraoperative maintenance: Propofol 80
fentanyl may be added as needed based on clinical symptoms.
Postoperative analgesia:
At the end of surgery: Fentanyl 0.5 µg/kg IV
Postoperative routine medication: Acetaminophen 10 mg/kg orally, q6h
Sponsors
Hubei Provincial Maternal and Child Health Care Hospital
Eligibility
Sex/Gender
All
Age
2 Years to 12 Years
Inclusion criteria
Inclusion criteria: Inclusion Criteria 1.Age 2-12 years, gender not limited 2.ASA classification I-II (good health or mild systemic disease) 3.Planned elective day surgery, estimated surgery time 30-120 minutes 4.Inguinal hernia repair 5.Circumcision 6.Excision of superficial masses 7.Informed consent signed by the child's legal guardian
Exclusion criteria
Exclusion criteria: 4.2 Exclusion Criteria 1.History of allergy or contraindication to any of the drugs mentioned in the study protocol 2.Severe hepatic or renal insufficiency (ALT/AST > 2 times the upper limit of normal) 3. Coagulation disorders (INR > 1.5, platelets 95th) 8. Positive predictor of difficult airway
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative nausea and vomiting (PONV) incidence;Recovery indicators;Analgesic usage;Patient family satisfaction;Cost-benefit indicators;Sleep quality assessment;Long-term behavioral change; | — |
Countries
China
Contacts
Public ContactShen Chan
Hubei Provincial Maternal and Child Health Care Hospital
Outcome results
None listed