Orthopedic lower limb surgery
Conditions
Interventions
Group D1:30 minutes before the start of the spinal anesthesia puncture, the patient was given a nasal spray of dexmedetomidine hydrochloride 25 µg.
Group D2:30 minutes before the start of the spinal anesthesia puncture, the patient was given a nasal spray of dexmedetomidine hydrochloride 50 µg.
Group NS:30 minutes before the start of spinal anesthesia puncture, the patient was given a nasal spray of 0.125 ml 0.9% sodium chloride solution.
Sponsors
Lu'an City Traditional Chinese Medicine Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Sign the informed consent form; 2. Patients scheduled for elective orthopedic lower limb surgery at this hospital; 3. Aged 18-65 years; 4. ASA classification (American Society of Anesthesiologists physical status) of I or II.
Exclusion criteria
Exclusion criteria: 1. History of long-term or recent use of antipsychotic, sedative, or analgesic drugs; 2. Severe heart, lung, liver, or kidney dysfunction (ASA grade III or above); 3. History of lumbar spine disorders and low back pain; 4. Abnormal coagulation function; 5. Currently participating in another clinical trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Assess the patient's degree of forgetfulness regarding the intrathecal anesthesia puncture procedure; | — |
Secondary
| Measure | Time frame |
|---|---|
| Sleep Quality Score: Richards-Campbell Sleep Questionnaire before surgery and three days after surgery;Incidence and severity of postoperative nausea and vomiting (PONV);Postoperative complications;Assess the patient's pain using the Visual Analog Scale (VAS, 0-10 points).;Days of hospitalization;Hospitalization expenses; | — |
Countries
China
Contacts
Public ContactChen Jianxiang
Lu'an City Traditional Chinese Medicine Hospital
Outcome results
None listed