Stroke
Conditions
Interventions
Control Group:The control group will receive 4 weeks of conventional rehabilitation and task-specific stair-ascent training. A dedicated sham coil that is identical in appearance and acoustic sensatio
coil placement and device parameter settings will be the same as those in the experimental group, thereby mimicking the stimulation procedure without delivering an effective magnetic field. This appro
Experimental group:The experimental group will receive an additional 4-week course of high-frequency repetitive transcranial magnetic stimulation (rTMS) on top of conventional rehabilitation and task-
Sponsors
Tianjin University of Sport
Eligibility
Sex/Gender
All
Age
40 Years to 70 Years
Inclusion criteria
Inclusion criteria: (1) Meets the diagnostic criteria for ischemic stroke revised at the 4th National Conference on Cerebrovascular Diseases, and the diagnosis is confirmed by cranial CT or MRI showing a unilateral lesion. (2) According to the Brunnstrom staging system, lower-limb motor recovery on the affected side is at least Stage V or above, indicating the presence of isolated movements and partial voluntary control of joint motion. (3) Without using any assistive devices, the patient is physically capable of independently completing at least three consecutive stair-ascent trials on a 10-cm step, to ensure safe completion of the biomechanical tests in this study. (4) Able to understand and comply with complex testing instructions and the training protocol. (5) Meets eligibility requirements based on international safety guidelines for transcranial magnetic stimulation. (6) All participants must sign an informed consent form approved by the Ethics Committee of Tianjin University of Sport, indicating voluntary participation and compliance with study procedures.
Exclusion criteria
Exclusion criteria: (1) Patients with hemorrhagic stroke, transient ischemic attack, traumatic brain injury, brain tumors, or other central nervous system disorders. (2) Patients with severe cardiac, hepatic, or renal insufficiency; severe uncontrolled hypertension; active infection; or hematologic diseases. (3) Patients with severe cognitive impairment, aphasia, severe visual field deficits, or other sensory system disorders that may substantially affect test performance. (4) Patients who are currently participating in other clinical trials or rehabilitation programs that may interfere with study outcomes, or who plan to undergo major changes in therapeutic regimens during the study period. (5) Patients with severe psychiatric disorders that preclude cooperation with study procedures, or those judged to have poor adherence and be unlikely to complete the full intervention and assessment protocol.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| mediolateral Displacement Range of the Center of Mass; | — |
Secondary
| Measure | Time frame |
|---|---|
| Hip flexion–extension range of motion;Knee flexion–extension range of motion;Ankle dorsiflexion–plantarflexion range of motion;Symmetry index of hip flexion–extension range of motion;Symmetry index of knee flexion–extension range of motion;Symmetry index of ankle dorsiflexion–plantarflexion range of motion;Vertical ground reaction force;Weight-bearing symmetry index;Center of pressure path length;Berg Balance Scale;Fugl-Meyer Lower Extremity Motor Function Assessment; | — |
Countries
China
Contacts
Public ContactHongshuai Leng
Tianjin University of Sport
Outcome results
None listed