Chronic obstructive pulmonary disease
Conditions
Interventions
Experimental group-Early behavioural and pharmacological intervention via digital technology:The behavioural and pharmacological intervention for COPD will be implemented online through digital system
Control-Genral education for COPD:Patients will receive routine education. In order to reflect real-world care for early diagnosed COPD, no additional interventions will be delivered to this group. Pa
Sponsors
China-Japan Friendship Hospital
Eligibility
Sex/Gender
All
Age
35 Years to 75 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria for high-risk screening population 1. aged 35-75 years 2. have never been diagnosed of COPD by physicians or suspected COPD but not have been clinically confirmed 3. local residents 4. willing to participate in screening and sign written informed consent form Inclusion criteria for early multifaceted interventional trial 1. aged 35-75 years 2. diagnosed of COPD by post spirometry test, with post-bronchodilator FEV1/FVC<0.7 3. local residents 4. can use smart phone 5. willing to accept comprehensive intervention for COPD and sign written informed consent form
Exclusion criteria
Exclusion criteria: Exclusion criteria for high-risk screening population 1. pregnancy, plan to be pregnant, or breastfeeding. 2. have the following contradictions to spirometry: (1) myocardial infarction, stroke, shock within recent 3 months; (2) severe cardiac dysfunction, severe arrhythmia, unstable angina within recent 4 weeks; (3) hemoptysis within recent 4 weeks; (4) undergo thoracic, abdominal, ophthalmologic surgeries within recent 3 months; (5) psychological illness; have hallucinations (auditory or visual), take antipsychotic medications, or require drug treatment for epileptic seizures. (6) severe cognitive impairment; (7) uncontrollable hypertension (SBP>200mmHg, DBP>100mmHg); (8) heart rate >120 beats/minute; (9) aortic aneurysm; (10) severe hyperthyroidism; (11) have a respiratory infectious disease in past 1 month, such as active tuberculosis, influenza, etc. 3. migrating population or plan to move recently. 4. decline or unable to sign informed consent. Exclusion criteria for early comprehensive interventions 1. pregnancy, plan to get pregnant, or breastfeeding. 2. primary diagnosis of asthma. 3. severe cognitive impairment. 4. have other diseases that damage lung severely and cause lung function decline, such as lung cancer resection, allergic bronchopulmonary aspergillosis, interstitial lung disease, etc. 5. active tuberculosis or other respiratory infectious diseases. 6. unable to complete spirometry. 7. being participating or will participate in other inhaler or behavioural interventional studies in the following two years. 8. migrating population or plan to move recently. 9. decline or unable to sign written informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Favourable lifestyle modification; | — |
Secondary
| Measure | Time frame |
|---|---|
| Change in pre-FEV1 during 12 months;Change in post-FEV1 during 12 months;Worsening of airflow obstruction;Annualised rate of mild-to-moderate acute exacerbation;Change in awareness of COPD; | — |
Countries
China
Contacts
Public ContactFen Dong
China-Japan Friendship Hospital
Outcome results
None listed