None
Conditions
Interventions
D4 Group:Collection of stem cells began on the fourth day of the mobilization process
D5 Group:Collection of stem cells began on the fifth day of the mobilization process
Sponsors
The First Affiliated Hospital of Chongqing Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1.Aged 18 to 60, both men and women are eligible; 2.Body weight >= 40 kg; 3.Related donors scheduled for PBSC mobilization and collection; 4.Willing and able to provide informed consent; 5.Willing to abide by the research plan and requirements; 6.On the fourth day of the mobilization, the number of peripheral blood CD34+ cells in the donors was greater than 40 cells/µL. 7.No G-CSF related grade 3 or higher adverse events occurred. 8.Peripheral venous access assessment is qualified (capable of supporting >=3-hour single blood collection);
Exclusion criteria
Exclusion criteria: 1.Pregnant and lactating women; 2.There is severe dysfunction of the heart, liver, kidneys and brain; 3.Allergic to G-CSF; 4.Those with active infectious diseases, autoimmune disorders, severe infections or uncontrolled mental illnesses; 5.Combine with other malignant tumors; 6.Currently participating in other clinical trials; 7.Unable to understand or unable to cooperate in completing the research plan; 8.Other situations that the researchers considered as not suitable for inclusion in the study;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Collection success rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Direct medical costs;The number of CD34+ cells in the collected product;Incidence of adverse reactions; | — |
Countries
China
Contacts
Public ContactYiying Xiong
The First Affiliated Hospital of Chongqing Medical University
Outcome results
None listed