Postoperative Psychomotor Recovery
Conditions
Interventions
Tegituridine group:Tegituridine for Postoperative Analgesia
Sufentanil group:Sufentanil for Postoperative Analgesia
Sponsors
Qingdao Municipal Hospital
Eligibility
Sex/Gender
All
Age
65 Years to No maximum
Inclusion criteria
Inclusion criteria: (1) Age >=65 years old; ASA Grade ?-? (2) Gender is not limited. (3) Select patients for laparoscopic gastrointestinal surgery; (4) FRAIL scale score >=3 points or clinical frailty score >=5 points; (5) Before the experiment, thoroughly understand the nature, significance, potential benefits, possible inconveniences and potential risks of the experiment, understand the research procedures and sign the informed consent form in person.
Exclusion criteria
Exclusion criteria: (1) Pregnant or lactating women and those who have a birth plan within 3 months; (2) Those with obvious respiratory and circulatory dysfunction, blood routine and blood biochemical indicators before surgery; (3) Those with severe neuropsychiatric diseases; (4) Patients with known hypersensitivity or contraindications to Tegituridine or any of its excipients; (5) Taking antidepressants, anxiolytics or other psychotropic drugs for a long time (more than 3 months); (6) Unable to understand or refuse to complete the questionnaire; (7) Patients who cannot obtain informed consent, or who are considered by the investigator to be inappropriate to participate in this trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative Psychomotor Recovery; | — |
Secondary
| Measure | Time frame |
|---|---|
| Pain VAS scores at 24 and 48 hours postoperatively;Incidence of postoperative complications at 24 and 48 hours.;Quality of Recovery-15 (QoR-15) scores at 24 and 48 hours postoperatively.;Length of patient hospital stay.; | — |
Countries
China
Contacts
Public ContactWang Bin
Qingdao Municipal Hospital
Outcome results
None listed