Hepatocellular carcinoma (HCC
Conditions
Interventions
Sponsors
The First Affiliated Hospital of Nanchang University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1.A patient who underwent focal hepatectomy in a tertiary hospital and was pathologically diagnosed with liver cancer; 2. At least one high recurrence risk factor is combined: multiple nodular tumors (>=2), maximum tumor diameter >5cm, accompanied by MVI, accompanied by satellite nodules, combined with large vessel tumor thrombus, poor pathological differentiation (Edmondson grade ? - ?); 3. After hepatectomy, the patient received adjuvant therapy with TKIs combined with ICIs, or did not receive any postoperative adjuvant therapy (except antiviral therapy).
Exclusion criteria
Exclusion criteria: 1.Recurrent liver cancer or pathologically confirmed as a mixed type of liver cancer and intrahepatic cholangiocarcinoma; 2. Combined with extrahepatic metastasis or other malignant tumors; 3. Combined with severe organ failure of the heart, lungs, brain, kidneys, etc. 4. Before the operation, anti-tumor treatment for liver cancer was carried out, including TACE, hepatic artery infusion chemotherapy, targeted therapy, immunotherapy, etc., except for antiviral treatment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Recurrence-free survival (RFS;Overall survival (OS; | — |
Secondary
| Measure | Time frame |
|---|---|
| Treat related adverse events; | — |
Countries
China
Contacts
Public ContactTan Yongming
The First Affiliated Hospital of Nanchang University
Outcome results
None listed