None
Conditions
Interventions
Control group (Fixed PEEP group):After the patient is transitioned to the prone position and recruitment maneuver is performed, the positive end-expiratory pressure will be set at 5 cmH2O until the en
Experimental group (Individualized PEEP group):After the patient is transitioned to the prone position and recruitment maneuver is performed, positive end-expiratory pressure titration will be conduct
Sponsors
The Second Affiliated Hospital of Wenzhou Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. ASA grade I - II 2. Patients scheduled for transforaminal lumbar interbody fusion in prone position under general anesthesia 3. BMI 18.5–27.9 kg/m²; 4. 18 years old <= age <= 80 years old.
Exclusion criteria
Exclusion criteria: 1. Patients who refuse to participate in the study; 2. Patients with severe preoperative cardiopulmonary diseases: chronic obstructive pulmonary disease (COPD), respiratory distress syndrome, bronchial asthma, pneumothorax/pulmonary bullae, pleural effusion, dependence on oxygen therapy or ventilatory support, history of previous pulmonary surgery, mechanical ventilation within 15 days prior to surgery, heart failure (New York Heart Association grade ? or ?).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Arterial oxygenation index; | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative pulmonary complications;PACU length of stay;Length of postoperative hospital stay;Positive end-expiratory pressure;Peak airway pressure;Plateau airway pressure;Dynamic compliance;Driving pressure;Pulse oxygen saturation;Heart rate;Mean arterial pressure; | — |
Countries
China
Contacts
Public ContactZheng Shengxing
The Second Affiliated Hospital of Wenzhou Medical University
Outcome results
None listed