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Observation on the Safety and Efficacy of Nasal Humidification Rapid Inflation Exchange Ventilation Technique in Clinical Anesthesia

The application of nasal humidified rapid airway exchange ventilation technique(THRAVE) in clinical anesthesia

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500115873
Enrollment
Unknown
Registered
2025-12-31
Start date
2025-01-06
Completion date
Unknown
Last updated
2026-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None

Interventions

Experiment 1: The nasopharyngeal tube asphyxia oxygenation group (Group N) :Transnasal humidified rapid-insufflation ventilatory exchange
Experiment 2: The nasopharyngeal tube asphyxia oxygenation group (Group N):Transnasal humidified rapid-insufflation ventilatory exchange
Experiment 3: The nasopharyngeal tube asphyxia oxygenation group (Group N) :Transnasal humidified rapid-insufflation ventilatory exchange
Experiment 4: The nasopharyngeal tube asphyxia oxygenation group (Group N) :Transnasal humidified rapid-insufflation ventilatory exchange
Experiment 1: Control group (Group C):Using a face mask that fits snugly against the face to breathe pure oxygen calmly
:Using a face mask that fits snugly against the face to breathe pure oxygen calmly

Sponsors

The Second Affiliated Hospital of Xi'an Jiaotong University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
5 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.Experiment 1: Application of Asphyxia Oxygenation Technique in Elderly Painless Gastrointestinal Endoscopy: ASA classification I-II, age >= 65 years old, BMI 19-25 kg/m^2. 2.Experiment 2: Application of Asphyxia Oxygenation Technique in Pediatric Bronchoscopy: ASA classification I-II, age 5-12 years old, BMI 19-25 kg/m^2. 3.Experiment 3: Application of Asphyxia Oxygenation Technique in Patients Undergoing Lobectomy with Single-Lung Ventilation: ASA classification I-II, age 18-65 years old, BMI 19-25 kg/m^2. 4.Experiment 4: The application effect of asphyxia oxygenation technology in hysteroscopic surgery: ASA classification I-?, age 18-65 years old, BMI 19-25 kg/m^2.

Exclusion criteria

Exclusion criteria: 1.Experiment 1: Patients with severe respiratory, cardiovascular and nervous system diseases, liver and kidney dysfunction, history of drug allergy, preoperative upper respiratory tract infection, and nasal obstruction. 2.Experiment 2: Patients with Severe respiratory system, cardiovascular system and nervous system diseases, congenital diseases, liver and kidney dysfunction, history of drug allergy, preoperative upper respiratory tract infection, or nasal obstruction. 3.Experiment 3: Patients with Severe cardiovascular and nervous system diseases, liver and kidney dysfunction, history of drug allergy, no upper respiratory tract infection before surgery, no nasal obstruction. 4.Experiment 4:Patients with respiratory system, cardiovascular system and nervous system diseases, liver and kidney dysfunction, history of drug allergy, and no upper respiratory tract infection before the operation.

Design outcomes

Primary

MeasureTime frame
The partial pressure of carbon dioxide was measured by percutaneous blood gas apparatus;The partial pressure of carbon dioxide was measured by percutaneous blood gas apparatus;The partial pressure of carbon dioxide was measured by percutaneous blood gas apparatus;The partial pressure of carbon dioxide was measured by percutaneous blood gas apparatus;

Countries

China

Contacts

Public ContactBai Jie

The Second Affiliated Hospital of Xi'an Jiaotong University

jiebai429@163.com+86 29 8767 9696

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026