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The effect of liposomal bupivacaine and bupivacaine hydrochloride on postoperative pain during laparoscopic repair of inguinal hernia in children with transverse abdominis muscle plane nerve block: a randomized, Open-label, parallel controlled clinical study

The effect of liposomal bupivacaine and bupivacaine hydrochloride on postoperative pain during laparoscopic repair of inguinal hernia in children with transverse abdominis muscle plane nerve block: a randomized, Open-label, parallel controlled clinical study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500115858
Enrollment
Unknown
Registered
2025-12-31
Start date
2026-01-01
Completion date
Unknown
Last updated
2026-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

hernia

Interventions

Experimental group (BL group):Use bupivacaine liposome injection for TAP nerve block.
Control group (BH group):Use bupivacaine injection for TAP nerve block.

Sponsors

Shanghai Children's Medical Center Affiliated to Shanghai Jiaotong University School of Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
6 Years to 18 Years

Inclusion criteria

Inclusion criteria: 1. Age between 6-18 years old; 2. American Society of Anesthesiologists (ASA) grades I-III; 3. Children diagnosed with inguinal hernia and scheduled for laparoscopic hernia repair surgery; 4. Willing to strictly follow the clinical trial protocol to complete this trial and voluntarily sign the informed consent form.

Exclusion criteria

Exclusion criteria: 1. Children with delayed intellectual development and inability to understand language; 2. Children who have recently undergone other surgeries; 3. There are contraindications for abdominal nerve block; 4. Patients with liver and kidney dysfunction; 5. Participants in other clinical trials; 6. Patients who refuse to sign informed consent forms or undergo postoperative pain relief.

Design outcomes

Primary

MeasureTime frame
Numerical Rating Scale of pain;The frequency of remedial analgesia during the patient's hospitalization;

Secondary

MeasureTime frame
The time of first receipt of remedial analgesia;

Countries

China

Contacts

Public ContactYunpeng Ouyang

Shanghai Children's Medical Center Affiliated to Shanghai Jiaotong University School of Medicine

ouyang19971118@163.com+86 175 2133 5430

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026