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Mechanism Research on the Influence of Intratumoral Microecological Changes in Gynecological Oncology on Tumor Occurrence, Development and Patient Prognosis

Mechanism Research on the Influence of Intratumoral Microecological Changes in Gynecological Oncology on Tumor Occurrence, Development and Patient Prognosis

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500115848
Enrollment
Unknown
Registered
2025-12-31
Start date
2025-12-31
Completion date
Unknown
Last updated
2026-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cervical cancer

Interventions

Case group (Intratumoral microecological community):None
Control group (Microecological community):None

Sponsors

Chongqing Health Center for Women and Children
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.Patients with gynecological malignant tumors: Patients who have been diagnosed with gynecological malignant tumors by histopathological examination; are at least 18 years old; have an expected survival period of = 3 months; have understood the entire study, signed the informed consent form, and voluntarily enrolled in the study. 2.Patients with benign gynecological tumors: Patients who have been diagnosed with benign gynecological tumors by histopathological examination; are at least 18 years old; have understood the entire study, signed the informed consent form, and voluntarily joined the group. 3.Health check-up participants: volunteers who are at least 18 years old; have no digestive system symptoms such as constipation or diarrhea within the recent 3 months; have understood the entire study, signed the informed consent form, and voluntarily joined the group.

Exclusion criteria

Exclusion criteria: 1.Patients with gynecological malignant tumors: those with other concurrent malignant tumor diseases; those with inflammatory bowel disease or other immune diseases; those with severe dysfunction of important organs such as the heart, liver, and kidneys; those who have used antibiotics, probiotics, or other drugs that may affect the microecology within the past month; those with mental illness or cognitive impairment who cannot cooperate in completing the study; those who refuse to participate in this study or fail to cooperate with follow-up. 2.Patients with benign gynecological tumors: those with comorbid inflammatory bowel disease or other immune diseases; those with severe dysfunction of important organs such as the heart, liver, and kidneys; those who have used antibiotics, probiotics, or other drugs that may affect the microecology within the past month; those with mental illness or cognitive impairment who cannot cooperate in completing the study; those who refuse to participate in this study or do not cooperate with follow-up. 3.Health check-up participants: those with comorbid inflammatory bowel disease or other immune diseases; those with other digestive system diseases; those with a history of digestive system surgery; those who have used antibiotics, probiotics, or other drugs that may affect the microecology within the past month.

Design outcomes

Primary

MeasureTime frame
Differences in intratumoral microecological diversity between cancerous tissue and adjacent tissue;

Secondary

MeasureTime frame
External control differences;Clinicopathological correlation;Differences in microecological composition;patients' prognostic;

Countries

China

Contacts

Public ContactChengzhi Zhao

Chongqing Health Center for Women and Children

330808042@qq.com+86 23 6370 2844

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026