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Mechanistic Study on Precise Immune Cell Phenotyping and Prognostic Prediction in Severe Infection

Mechanistic Study on Precise Immune Cell Phenotyping and Prognostic Prediction in Severe Infection

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500115845
Enrollment
Unknown
Registered
2025-12-31
Start date
2026-01-01
Completion date
Unknown
Last updated
2026-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sepsis

Interventions

Sponsors

The Second Affiliated Hospital of Wenzhou Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.Age >= 18 years; 2.Diagnosed with severe infection or sepsis (according to the Sepsis-3 criteria) within 24 hours after ICU admission; 3.Planned to receive standard treatment with an expected hospital stay of >= 3 days; 4.Able to provide written informed consent, or consent obtained from a legal representative.

Exclusion criteria

Exclusion criteria: 1.Use of glucocorticoids or other immunosuppressive agents for >= 7 days prior to enrollment; 2.Presence of end-stage malignancy, AIDS, or other severe immunodeficiency disorders; 3.Pregnant or breastfeeding women; 4.Hospitalized for >= 48 hours prior to ICU admission; 5.Refusal to participate or withdrawal of informed consent;

Design outcomes

Primary

MeasureTime frame
Immunophenotypic Association Analysis;

Secondary

MeasureTime frame
Radiomics Combined Analysis;

Countries

China

Contacts

Public ContactShengwei Jin

The Second Affiliated Hospital of Wenzhou Medical University

jinshengwei69@163.com+86 136 1666 3961

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026