Adolescent Depressive Disorder with Disordered Eating Behaviors
Conditions
Interventions
No Abnormal Eating Behavior - Placebo Group:placebo
Abnormal Eating Behavior - Placebo Group:placebo
No Abnormal Eating Behavior - Probiotic Group:Probiotic Intervention
Abnormal Eating Behavior - Probiotic Group:Probiotic Intervention
Sponsors
Shandong mental health center
Eligibility
Sex/Gender
All
Age
12 Years to 18 Years
Inclusion criteria
Inclusion criteria: 1.Aged 12-18 years; 2.Meets ICD-10 diagnostic criteria for depressive disorder. 3.No history of treatment or interventions (e.g., electroconvulsive therapy) before enrollment. 4.Capacity to comprehend and cooperate with the entire study procedure.
Exclusion criteria
Exclusion criteria: 1.Diagnosed with other major psychiatric disorders (e.g., schizophrenia, bipolar disorder) or eating disorders. 2.Has severe or unstable physical illnesses. 3.Has taken medications affecting immunity or appetite within the past month. 4.Unable to cooperate with the assessments.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Gut Microbiota Composition and Diversity (16SrDNA Sequencing);Yale Food Addiction Scale (YFAS) Score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Dutch Eating Behaviours Questionnaire, DEBQ;17-item Hamilton Depression Scale,HAMD;Hamilton Anxiety Rating Scale,HAMA; | — |
Countries
China
Contacts
Public Contactzhang yue
Shandong mental health center
Outcome results
None listed