Skip to content

Protective Effects of Electrical Impedance Tomography-Guided PEEP Titration on the Lungs During Mechanical Ventilation in Children Undergoing Open Abdominal Surgery Under General Anesthesia

Protective Effects of Electrical Impedance Tomography-Guided PEEP Titration on the Lungs During Mechanical Ventilation in Children Undergoing Open Abdominal Surgery Under General Anesthesia

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500115812
Enrollment
Unknown
Registered
2025-12-31
Start date
2026-01-01
Completion date
Unknown
Last updated
2026-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None

Interventions

Electrical Impedance Tomography (EIT)-titrated PEEP group (E group, PEEP = PEEP_EIT):Electrical Impedance Tomography (EIT)-titrated PEEP during the operation
conventional PEEP group (C group, PEEP = 4 cmH?O):PEEP=4cmH2O throughout the operation

Sponsors

Beijing Children’s Hospital, Capital Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
1 Years to 6 Years

Inclusion criteria

Inclusion criteria: (1) Age >= 1 year and = 2 hours; (4) Gender unrestricted; (5) American Society of Anesthesiologists (ASA) physical status classification <= III.

Exclusion criteria

Exclusion criteria: (1) Body Mass Index (BMI) = 97th percentile (according to CDC child growth standards); (2) Severe respiratory tract infection within the past 4 weeks; (3) History of major cardiothoracic surgery; (4) History of complex abdominal surgery within the past 3 months; (5) Inability to place EIT electrodes on the chest (e.g., significant thoracic deformity, local scarring, or infection); (6) Presence of structural lung disease or uncontrolled asthma; (7) Neuromuscular disease

Design outcomes

Primary

MeasureTime frame
the Modified Lung Ultrasound Score (MLUS) measured at 30 minutes after tracheal extubation;

Secondary

MeasureTime frame
Dorsal fraction of ventilation;

Countries

China

Contacts

Public ContactZenghua Xu

Beijing Children’s Hospital, Capital Medical University

xuzenghua.2007@163.com+86 137 1696 0279

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026