Neurofibromatosis type 1
Conditions
Interventions
Gold Standard:Concurrent MRI findings
Sponsors
The Second Affiliated Hospital of Wenzhou Medical University
Eligibility
Sex/Gender
All
Age
No minimum to 18 Years
Inclusion criteria
Inclusion criteria: 1. Age 0–18 years, meeting the 2021 International Diagnostic Criteria for NF1; 2. Complete ultrasound examination and clinical data; 3. Complete and traceable case records.
Exclusion criteria
Exclusion criteria: 1.Complicated with other hereditary diseases (e.g., Noonan syndrome, Legius syndrome) or malignant tumors (e.g., rhabdomyosarcoma); 2.Previous surgical resection of critical lesions may affect the baseline data for ultrasonic assessment. 3.Substandard ultrasonic image quality (e.g., failure to clearly display the target area due to obstruction by obesity or severe intestinal gas); 4.Severe dysfunction of heart, liver, kidney and other organs;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Ultrasonic Characteristics of Neurofibromatosis Type 1;Database extraction: Demographic data, clinical characteristics, ultrasound parameters, MRI findings, and follow-up outcomes;Consistency Kappa value; | — |
Countries
China
Contacts
Public ContactLuo Hongxia
The Second Affiliated Hospital of Wenzhou Medical University
Outcome results
None listed