Uremic stage of chronic renal failure
Conditions
Interventions
HD Group:In the first week, HD treatment was received, followed by a two-week elution period (i.e., recovery to conventional HD). In the fourth week, artificial IHDF treatment was received. At the end
IHDF Group:In the first week, artificial IHDF treatment was received, followed by a two-week elution period (i.e., recovery to conventional HD). In the fourth week, HD treatment was received. At the e
Sponsors
Nanchang University First Affiliated Hospital Gaoxin Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: (1) Have received regular hemodialysis in our hospital for more than 3 months; (2) It conforms to the fourth clinical classification of hemodialysis combined with hypertension in the "Standard Operating Procedures for Blood Purification", namely the RAAS/SNS over-activation type; (3) Voluntarily sign the informed consent form and agree to participate in the research; (4) Age: 18 to 75 years old.
Exclusion criteria
Exclusion criteria: (1) Combined with malignant tumors; (2) Severe heart or lung system diseases have occurred within three months, such as heart failure, malignant arrhythmia, respiratory failure, etc. (3) Those with a history of neurological or mental system diseases; (4) Severe infection; (5) Patients with secondary hypertension other than renal hypertension who meet the fourth clinical classification of hypertension combined with hemodialysis as stipulated in the "Standard Operating Procedures for Blood Purification"; (6) Patients whose antihypertensive regimens were adjusted during the trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The fluctuation range of systolic blood pressure/diastolic blood pressure; | — |
Secondary
| Measure | Time frame |
|---|---|
| Adverse events;Serious adverse events;SNS, RAAS axis activity, endothelial function, vascular function;Ultrafiltration compliance rate;The usage rate of antihypertensive drugs;The incidence of hypertension during dialysis; | — |
Countries
China
Contacts
Public ContactFeifei Wu
Nanchang University First Affiliated Hospital Gaoxin Hospital
Outcome results
None listed