None
Conditions
Interventions
Control group:New double-sleeve endotracheal tube with antimicrobial coating
Observation group:Use of conventional endotracheal intubation
Sponsors
The First Hospital Of Jiaxing
Eligibility
Sex/Gender
All
Age
18 Years to 100 Years
Inclusion criteria
Inclusion criteria: 1.Endotracheal intubation; 2.Age >= 18 years old; 3.No significant injury or bleeding in the mouth; 4.Authorized person informed consent;
Exclusion criteria
Exclusion criteria: 1.Patients who have had an acute or chronic respiratory or pulmonary infection before the establishment of an artificial airway; 2.Trauma or surgery to the oropharynx, trachea, or esophagus; 3.Patients with advanced cachexia from tumors; 4.The ICU stay < 5 days;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| C-reactive protein, interleukin-6, procalcitonin, tumor necrosis factor-a;Shannon index, Simpson index;The abundance of bacterial flora and the number of pathogenic bacteria changed; | — |
Secondary
| Measure | Time frame |
|---|---|
| General Information; | — |
Countries
China
Contacts
Public ContactSheng Han
The First Hospital Of Jiaxing
Outcome results
None listed