Vitreoretinal Diseases
Conditions
Interventions
F6H8 group:Intraoperative application of perfluorohexyloctane eye drops (F6H8) to maintain corneal clarity.
BSS group:Intraoperative application of balanced salt solution (BSS) to maintain corneal clarity.
Sponsors
The First Affiliated Hospital of Xi 'an Jiaotong University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: (1) Scheduled to undergo vitreoretinal surgery or silicone oil removal surgery; (2) Age between 18 and 75 years; (3) Voluntary participation in the study and provision of signed informed consent.
Exclusion criteria
Exclusion criteria: (1) Scheduled to undergo combined cataract and vitrectomy surgery; (2) Requirement for combined keratoplasty during surgery; (3) Diagnosis of dry eye disease based on preoperative examination; (4) History of keratitis or uveitis prior to surgery; (5) Corneal endothelial cell count < 1200 cells/mm²; (6) Long-term use of topical eye drops or long-term wear of corneal contact lenses; (7) Allergy to the active pharmaceutical ingredient used in this study; (8) Women who are pregnant or breastfeeding; (9) Any other disease, condition, or social factor that, in the investigator's judgment, may affect subject safety or interfere with the study results.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Intraoperative Corneal Clarity Maintenance Time; | — |
Secondary
| Measure | Time frame |
|---|---|
| Breakup time (BUT);Corneal fluorescein staining (CFS);Schirmer II test (SIIt); | — |
Countries
China
Contacts
Public ContactLiu Xuan
The First Affiliated Hospital of Xi 'an Jiaotong University
Outcome results
None listed