Children with congenital heart disease
Conditions
Interventions
Bupivacaine liposome group:After anesthesia, anterior serratus nerve block was performed with 0.25% bupivacaine liposomes at a dose of 0.4ml/kg
Ropivacaine group:After anesthesia, anterior serratus nerve block was performed at a concentration of 0.25% ropivacaine and a dose of 0.5ml/kg
Control group:Perform anterior serratus nerve block after anesthesia and administer physiological saline
Sponsors
Fuwai Central China Cardiovascular Hospital
Eligibility
Sex/Gender
All
Age
No minimum to 18 Years
Inclusion criteria
Inclusion criteria: 1.0-18 years old 2. Planned surgery for congenital heart disease under general anesthesia 3. ASA (II-IV level) 4. Parents voluntarily sign an informed consent form
Exclusion criteria
Exclusion criteria: 1.Patients with combined mental system disorders and cognitive dysfunction; 2. Known allergy to bupivacaine or other amide local anesthetics 3. Severe liver and kidney dysfunction 4. Patients with chest deformities who cannot undergo nerve block 5. Infected individuals at the puncture site
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The dosage of sufentanil per kilogram of body weight during surgery and within 72 hours after surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| Flacc pain score, Ramsay sedation score;Heart rate and mean arterial blood pressure;The time of first compression of the analgesic pump (counted from the time of extubation after surgery), the total number of compressions of the analgesic pump within 72 hours after surgery, and the effective number of compressions of the analgesic pump within 72 hours after surgery; | — |
Countries
China
Contacts
Public ContactHongqi Lin
Fuwai Central China Cardiovascular Hospita
Outcome results
None listed