coronary artery spasm
Conditions
Interventions
Colchicine Group:Colchicine 0.5 mg qd.
Conventional Treatment Group:Placebo 0.5 mg qd.
Control Group:Nothing
Sponsors
The First People's Hospital of Nantong
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Ages 18 to 65; 2. According to the diagnostic criteria of the 2013 Japanese Circulation Society (JCS) guidelines for the diagnosis and treatment of coronary spastic angina. 3. Cardiac function: LVEF > 45%.
Exclusion criteria
Exclusion criteria: 1. Age >65 years; 2. Acute infectious disease within the past 4 weeks; 3. Chronic infectious disease; 4. Use of anti-inflammatory or immunomodulatory drugs within 4 weeks; 5. History of myocardial infarction within 4 weeks; 6. Surgery within the past 4 weeks; 7. Peripheral arterial disease or neoplastic diseases; 8. Severe cardiac insufficiency with left ventricular ejection fraction (LVEF) <45%; 9. Hypertrophic obstructive cardiomyopathy or valvular heart disease; 10. Bradyarrhythmia with a history of syncope or Adams-Stokes syndrome attacks; 11. Poor-quality CCTA images.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Composite incidence of MACE; | — |
Secondary
| Measure | Time frame |
|---|---|
| Fat attenuation index;hs-CRP;IL-6; | — |
Countries
China
Contacts
Public ContactZhenqiang Sheng
The First People's Hospital of Nantong
Outcome results
None listed