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Efficacy of Repetitive Transcranial Magnetic Stimulation in Preventing Postoperative Delirium in Elderly Patients Undergoing Three-Incision (Cervical, Thoracic, and Abdominal) Esophagectomy: A Randomized Controlled Trial

Efficacy of Repetitive Transcranial Magnetic Stimulation in Preventing Postoperative Delirium in Elderly Patients Undergoing Three-Incision (Cervical, Thoracic, and Abdominal) Esophagectomy: A Randomized Controlled Trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500115718
Enrollment
Unknown
Registered
2025-12-30
Start date
2026-01-01
Completion date
Unknown
Last updated
2026-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative delirium

Interventions

Pseudostimulation rTMS group:Undergo the same RMT measurement with the coil in the same position, but without active stimulation.

Sponsors

Army Medical Center of PLA
Lead Sponsor

Eligibility

Sex/Gender
All
Age
65 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.Patients aged 65 years or older, with an American Society of Anesthesiologists (ASA) physical status grade <=III, and scheduled for a three-port (neck, thorax, and abdomen) partial esophagectomy were included.

Exclusion criteria

Exclusion criteria: 1. History of mental illness, cognitive impairment, or inability to comprehend assessment tools; 2. History of neurological or psychiatric disorders; 3.Brain or scalp injuries; 4.Substance abuse (including drugs/alcohol); 5.Visual/hearing impairments or communication difficulties; 6.Metal implants, skin lesions, or hypersensitivity to surface electrodes; 7.Severe cardiovascular disease or significant liver/renal dysfunction; 8.Concurrent participation in other clinical trials.

Design outcomes

Primary

MeasureTime frame
The incidence of delirium within 7 days after surgery;

Secondary

MeasureTime frame
Incidence of neurocognitive disorders 30 days post-surgery;Postoperative day 3 QOR-15 quality of life score;Postoperative brain-derived neurotrophic factor (BDNF);Postoperative adverse reactions;Postoperative pulmonary complications;

Countries

China

Contacts

Public ContactQingxiang Mao

Army Medical Center of PLA

maomaosmmu@126.com+86 13594054231

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026