myopia
Conditions
Interventions
eyelid-wipe group:In addition to routine orthokeratology (OK) lens wear and care, participants will use OCUFACE? eyelid-cleaning wipes once daily, before lens wear at night, for one month.
control group:Participants will receive only standard OK lens wear and care instructions, without the use of any additional eyelid-cleaning products.
Sponsors
Guangzhou Aier Eye Hospital
Eligibility
Sex/Gender
All
Age
8 Years to 12 Years
Inclusion criteria
Inclusion criteria: 1. Children and adolescents aged 8–12 years; 2. Spherical equivalent refractive error between –1.00 D and –6.00 D, with astigmatism = 1.50 D; 3. No significant dry eye–related symptoms; 4. No severe ocular surface or eyelid diseases (e.g., active blepharitis, keratoconjunctivitis, severe allergic conjunctivitis, etc.); 5. Suitable candidates for orthokeratology for refractive correction; 6. No regular use of other eyelid-cleaning products or anti-inflammatory medications (including corticosteroids, cyclosporine, tacrolimus, etc.) within the past 3 months; 7. The legal guardian of the participant provides informed consent, and the participant is willing to comply with follow-up visits and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Presence of severe corneal staining, corneal ulcer, keratoconus, or other significant corneal diseases; 2. History of ocular surgery or severe ocular trauma; 3. Presence of systemic diseases that may affect the tear film or ocular surface (e.g., Sjögren’s syndrome, rheumatoid arthritis, etc.); 4. Known allergy to any component of the eyelid-cleaning wipes; 5. Planned change of orthokeratology lens brand or care solution during the study period; 6. Participation in any other interventional clinical study within the past 3 months; 7. Poor compliance; 8. Any other condition that the investigator considers inappropriate for inclusion in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| NITBUT;Change in eyelid margin cleanliness/secretion score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Change in tear break-up time;Change in tear meniscus height;Lipid layer thickness;Meibomian gland expressibility;Meibomian gland dropout ratio;Oxford corneal staining score;MMP-9 inflammatory test results;Change in OSDI total score;Change in contact lens wearing comfort; | — |
Countries
China
Contacts
Public ContactXiaoxiao Zhang
Guangzhou Aier Eye Hospital
Outcome results
None listed