None
Conditions
Interventions
Observation group:N/A
Sponsors
The Second Affiliated Hospital of Chongqing Medical University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Inclusion Criteria for Mothers:No use of any antibiotics or probiotic products within 1 month prior to enrollment. Inclusion Criteria for Infants: No restriction on gender; Born via natural delivery; Healthy, full-term infants; Breastfeeding has been initiated before the first sampling (within 7 days after birth), and the mother is willing to continue breastfeeding subsequently.
Exclusion criteria
Exclusion criteria: Gestational diabetes, hypertension, coronary heart disease, acute infectious diseases (especially tuberculosis, viral hepatitis, HIV infection), cancer, postpartum depression, nipple or breast inflammation, having received hormone therapy within one month prior to recruitment, inability to communicate or answer questionnaires, and currently participating in nutritional or drug intervention studies.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 2'-Fucosyllactose;3-Fucosyllactose;3'-Sialyllactose sodium salt;6'-Sialyllactose sodium salt;Lacto-N-tetraose;Lacto-N-neotetraose;Fecal microbiome;Fecal metabolome;Breast milk microbiome;Breast milk metabolome;Vaginal microbiota;Blood metabolome; | — |
Countries
China
Contacts
Public ContactXiaojing Dong
The Second Affiliated Hospital of Chongqing Medical University
Outcome results
None listed