Patients with aplastic anemia (including severe AA and non-severe AA)
Conditions
Interventions
Romiplostim N01 treatment group:NA
Sponsors
Hebei Province Hospital of Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. >=18 years old, gender not limited; 2. Both newly diagnosed and previously treated patients with aplastic anemia (AA)(including SAA and NSAA) are eligible for enrollment; 3. Voluntarily sign a written informed consent form and be able to comply with the visitation and related procedures stipulated in the plan.
Exclusion criteria
Exclusion criteria: 1. Unable to comply with the study plan or procedures; 2. Congenital aplastic anemia (e.g., Fanconi anemia, congenital parakeratosis); 3. Patients who have previously received Romiplostim; 4. According to the investigator's judgment, those with concomitant diseases that seriously endanger patient safety or affect the patient's completion of the study; 5. The investigators considered patients unsuitable for inclusion in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The hematological response rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| The hematological responce rate and complete responce rate;Duration of hematological responce;The changes in reticulocytes and T-lymphocyte subsets of the patients;Evaluation of clonal evolution;The complete hematological responce rate ;The long-term safety and tolerance of Romiplostim N01; | — |
Countries
China
Contacts
Public ContactZijing Guo
Hebei Province Hospital of Chinese Medicine
Outcome results
None listed