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Analysis of the effect of diaphragm ultrasound assessment combined with SBT criteria on the success rate and prognosis of extubation in critically ill patients in neurosurgery: a multicenter prospective randomized controlled study

Analysis of the Effect of Nursing Team-Based Diaphragmatic Ultrasound Assessment Combined with SBT Criteria on Extubation Success Rate and Prognosis in Neurosurgical Critically Ill Patients: A Multicenter Prospective Randomized Controlled Study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500115686
Enrollment
Unknown
Registered
2025-12-30
Start date
2025-12-30
Completion date
Unknown
Last updated
2026-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mechanical ventilation dependence and difficult weaning in neurosurgical critically ill patients

Interventions

DTE+DE group:Intervention process based on joint assessment of diaphragmatic thickening rate (DTF) and diaphragmatic mobility (DE).
DTE group:Intervention process based on the assessment of diaphragmatic thickening fraction (DTF)
Control group:Control group: Traditional SBT process

Sponsors

Shanghai General Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Meet the diagnostic criteria for neurosurgical critically ill patients in the "Expert Consensus on Neurosurgical Critical Care Management in China (2020 Edition)"; 2. Patients aged >= 18 years who were continuously admitted to the ICU during the study period; 3. Mechanical ventilation time >= 24h.

Exclusion criteria

Exclusion criteria: 1. Trauma fixation, skin and other reasons affect the movement of the diaphragm and its ultrasound examination; 2. Patients who received invasive or non-invasive ventilation treatment before admission to the hospital; 3. Pregnant or lactating women; 4. No SBT was performed or passed within 2 weeks after mechanical ventilation; 5. Tracheotomy was performed during the experiment. 6. During the research period, family members or patients request to withdraw from the experiment.

Design outcomes

Primary

MeasureTime frame
The success rate of the first weaning;

Secondary

MeasureTime frame
length of hospital stay;Total medical expenses;Duration of mechanical ventilation;Incidence rate of VAP;

Countries

China

Contacts

Public ContactFei Kaihong

Shanghai General Hospital

cjxiaojinyu@126.com+86 21 6324 0090

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026