Intrauterine Adhesions
Conditions
Interventions
Normal control group:None
Mild IUA group:None
Moderate IUA group:None
Severe IUA group:None
Sponsors
Chongqing Health Center for Women and Children
Eligibility
Sex/Gender
Female
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: 1. Control group: Age 18–40 years, with fertility requirements; regular menstrual cycles (21–35 days); undergoing hysteroscopy for other benign lesions (e.g., a single endometrial polyp <2 cm in diameter not involving the fundus or cornua), with intraoperative confirmation of no uterine adhesions; preoperative 3D ultrasound showing regular uterine cavity morphology and continuous endometrial line without interruption; postoperative pathology of the polyp confirmed as benign with no need for hormonal therapy; signed informed consent and voluntarily participated in this study. 2. IUA disease group: Age 18–40 years, with fertility requirements; regular menstrual cycles (21–35 days); diagnosed with IUA via outpatient or inpatient hysteroscopy and planned for TCRA surgery; signed informed consent and voluntarily participated in this study.
Exclusion criteria
Exclusion criteria: 1. Pregnant or lactating; 2. History of hormone use within the past 3 months (e.g., oral contraceptives, progestogens); 3. Concurrent malignant or suspected malignant endometrial lesions; 4. Concurrent other uterine conditions that may severely affect uterine cavity morphology or interfere with SWE measurements, such as large fibroids (diameter >4 cm), diffuse or severe adenomyosis; 5. History of pelvic radiation or chemotherapy; 6. Known systemic connective tissue disease; 7. Inability to cooperate with transvaginal ultrasound examination.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| SWE Diagnostic Efficacy (Grading of IUA Severity);IUA Recurrence Rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative Pregnancy Outcomes;AI Model Predictive Efficacy (Natural Pregnancy Rate within 1 Year Post-surgery);Correlation between SWE Parameters and Adhesion Tissue Pathology;Postoperative Menstrual Volume Improvement; | — |
Countries
China
Contacts
Public ContactChi Yugang
Chongqing Health Center for Women and Children
Outcome results
None listed