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Study on the clinical efficacy and amnesia effect of remimazolam in the prevention and treatment of catheter-related bladder discomfort (CRBD)

Study on the clinical efficacy and amnesia effect of remimazolam in the prevention and treatment of catheter-related bladder discomfort (CRBD)

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500115632
Enrollment
Unknown
Registered
2025-12-29
Start date
2026-01-01
Completion date
Unknown
Last updated
2026-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

catheter-related bladder discomfort

Interventions

Control group:no
Remimazolam group:remimazolam

Sponsors

Wuxi People’s Hospital
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
20 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Age >=20 years old and <=65 years old, male; 2. Patients who undergo non-urological surgery and require indwelling urinary catheters; 3. ASA grade?-?; 4. Agree to participate in this study and sign the informed consent form;

Exclusion criteria

Exclusion criteria: 1. Refuse to participate in this study; 2. ASA grade IV or above or planned to be transferred to the ICU after surgery; 3. BMI =30kg/m ²; 4. History of drug abuse or allergy to narcotic drugs; 5. Severe cardiovascular and nervous system diseases, and severe liver and kidney dysfunction; 6. There are preoperative neurogenic bladder/intestinal dysfunction, bladder output obstruction, and overactive bladder; 7. Have participated in other studies within the past 30 days; 8. Those with a history of abnormal surgical anesthesia recovery; 9. Those who are predicted to have or have had difficult airways, such as modified Mallampati‘s classification grade III-IV; 10. Pregnant, lactating or other subjects who the researchers consider unsuitable to participate in this study.

Design outcomes

Primary

MeasureTime frame
CRBD classification;

Secondary

MeasureTime frame
Indwelling time of the urinary catheter;Degree of urethral discomfort;The number of times for postoperative remedial analgesia;Awakening Score;The satisfaction of patients;awakening time;Memory status;sleep quality;Sedation level;Blood pressure (SBP, MAP,DBP), HR, SPO2, BIS;The number of compressions of the analgesic pump;

Countries

China

Contacts

Public ContactXin Zhang

Wuxi People’s Hospital

xinzhang3@njmu.edu.cn+86 510 85351555

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026