epilepsy
Conditions
Interventions
Drug-refractory epilepsy group:None
Sponsors
Xuanwu Hospital, Capital Medical University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. No restrictions on age or gender; 2. Clinically diagnosed with drug-refractory epilepsy and planned to undergo SEEG evaluation; 3. Agree to participate in the study and sign a written informed consent form; 4. Those whose SEEG implanted electrodes cover the temporal lobe, frontal lobe, insula, or language-related brain regions are preferred for inclusion.
Exclusion criteria
Exclusion criteria: 1. Those with obvious cognitive impairment or mental disorders who are unable to complete tasks or have difficulty understanding task instructions; 2. Those with severe hearing impairment who cannot normally perceive auditory stimuli; 3. Subjects whose epileptic seizures are induced by auditory stimuli. 4. Those who develop postoperative complications (such as intracranial hemorrhage, infection) that affect the safety of the study; 5. Those who cannot cooperate in completing language and auditory tasks while awake or under anesthesia; 6. Pregnant or lactating women; 7. Other situations that the researchers consider inappropriate for participation in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Inter-electrode functional connectivity index (coherence); | — |
Secondary
| Measure | Time frame |
|---|---|
| Differences in event-related potential (ERP) waveforms;Task related time-frequency characteristics;Spatial distribution of activated electrodes; | — |
Countries
China
Contacts
Public ContactShu Wei
Xuanwu Hospital, Capital Medical University
Outcome results
None listed