Skip to content

Safety and Efficacy of Percutaneous Sphere Resection (PSR) vs. Thoracoscopic Sublobectomy for Subcentimeter Pulmonary Nodules in Elderly Patients: a Prospective Non-randomized Controlled Study

Safety and Efficacy of Percutaneous Sphere Resection (PSR) vs. Thoracoscopic Sublobectomy for Subcentimeter Pulmonary Nodules in Elderly Patients: a Prospective Non-randomized Controlled Study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500115570
Enrollment
Unknown
Registered
2025-12-29
Start date
2026-01-01
Completion date
Unknown
Last updated
2026-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Subcentimeter pulmonary nodules

Interventions

Percutaneous sphere resection group (PSR group):Percutaneous sphere resection was peformed.
Thoracoscopic sublobectomy group (wedge resectionor segmentectomy) (Sub-L group):Thoracoscopic sublobectomy (wedge resectionor segmentectomy) was peformed.

Sponsors

West China Hospital of Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
60 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.Age >=60 years old; 2.Chest CT shows that the diameter of the target nodule is >=5mm and <=10mm, and imaging suggests pre-invasive lesions or early tumors. 3.Be able to understand the research content and sign the informed consent form, and abide by the follow-up requirements.

Exclusion criteria

Exclusion criteria: 1.Pregnant or lactating women; 2.Severe cardiopulmonary insufficiency or inability to tolerate anesthesia/surgery (ASA> grade 3); 3.Combined with active pulmonary infection; 4.Coagulation dysfunction/inability to suspend anticoagulant therapy (platelet count 16 seconds) 5.Previous history of lung surgery or chest radiotherapy; 7.There is evidence of extensive metastatic disease.

Design outcomes

Primary

MeasureTime frame
Pulmonary function three months after the operation;

Secondary

MeasureTime frame
Success rate of operation;The duration of the operation;Thoracic catheterization time and drainage volume;Postoperative hospital stay duration;Intrapulmonary healing rate;Postoperative pain score;Quality of life score;Postoperative pulmonary function;The incidence of complications within 30 days after the operation;Tumor recurrence rate;

Countries

China

Contacts

Public ContactMei Jiandong

West China Hospital of Sichuan University

jiandongmei@aliyun.com+86 189 8060 1762

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026