Colorectal cancer
Conditions
Interventions
Low Muscle Mass Group:Nerve block with different concentrations of ropivacaine
Normal Muscle Mass Group:Nerve block with different concentrations of ropivacaine
Sponsors
First Hospital of Jilin University
Eligibility
Sex/Gender
All
Age
65 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.The patient has a full understanding of the study, voluntarily participates in it, and signs the informed consent form. 2.Patients who are scheduled to undergo laparoscopic colon or rectal cancer surgery. 3.American Society of Anesthesiologists (ASA) physical status classification is Grade ?–?. 4.Aged 65 years or above, regardless of gender.
Exclusion criteria
Exclusion criteria: 1.Patients with neuromuscular diseases, cognitive dysfunction, allergies to anesthetic drugs, a history of opioid abuse, coagulation disorders, or liver and kidney failure. 2.Infection or damage near the puncture site. 3.Cases where the patient refuses to sign the informed consent form to participate in the study. 4.Other circumstances that the researchers deem inappropriate for participation in this trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Whether the block is successful or not,Minimum Effective Concentration of Ropivacaine; | — |
Secondary
| Measure | Time frame |
|---|---|
| The NRS scores of patients at rest and during movement were measured at 3, 6, 12, and 24 hours postoperatively.;Intraoperative opioid consumption;Total postoperative opioid consumption;Number of effective presses of the postoperative analgesic pump;Incidence of adverse reactions such as postoperative nausea, vomiting and dizziness;Plasma ropivacaine concentration;Time to first ambulation;Patient satisfaction score; | — |
Countries
China
Contacts
Public ContactLiZhiwen
First Hospital of Jilin University
Outcome results
None listed